Biological applications of biosynthesized silver nanoparticles through the utilization of plant extracts

  • Rouhollah Heydari * Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
Keywords: Silver nanoparticles, Plant extract, Antimicrobial, Antioxidant, Anticancer

Abstract

Widespread uses of metallic nanoparticles, especially silver nanoparticles (AgNPs) in biology, pharmaceuticals, and medicine lead to the development of biosynthesis methods that are in turn utilized to prepare these nanoparticles. Among the biosynthesis methods, which are used to prepare nanoparticles, the plant-mediated methods have gained great attention due to several advantages such as cost-effectiveness, availability, eco-friendliness and nontoxicity of plants. Moreover, plant extracts are rich in different compounds which act as inhibitory and capping agents. For these reasons, plant-mediated methods can be potentially used for large-scale production of nanoparticles with different properties. The present article focuses on plant-mediated AgNPs using various plants and their biological applications such as antimicrobial, antioxidant, anticancer, anti-inflammatory, hepatoprotective and antilarvicidic properties.

References

Altavilla C, Ciliberto E. Inorganic Nanoparticles: Synthesis, Applications, and Perspectives, CRC Press, Taylor & Francis Group, 2011, USA.

Kesava Kumar CM, Yugandhar P, Savithramma N. Biological synthesis of silver nanoparticles from Adansonia digitata L. fruit pulp extract, characterization, and its antimicrobial properties. J Intercult Ethnopharmacol. 2016;5:79-85.

Yugandhar P, Savithramma N. Leaf assisted green synthesis of silver nanoparticles from Syzygium alternifolium Wt. Walp. Characterization and antimicrobial studies. Nano Biomed Eng. 2015;7:29-37.

Seema G, Amrish C, Avijit M, Rupa M. Green synthesis of silver nanoparticles using Arnebia nobilis root extract and wound healing potential of its hydrogel. Asian J Pharm. 2014;8:95-101.

Sundaravadivelan C, Nalini Padmanabhan M, Sivaprasath P, Kishmu L. Biosynthesized silver nanoparticles from Pedilanthus tithymaloides leaf extract with anti-developmental activity against larval instars of Aedes aegypti L. Diptera; Culicidae. Parasitol Res. 2013;112:303-11.

Swamy MK, Sudipta KM, Jayanta K, Balasubramanya S. The green synthesis, characterization, and evaluation of the biological activities of silver nanoparticles synthesized from Leptadenia reticulata leaf extract. Appl Nanosci. 2014;5:73-81.

Vasanth K, Ilango K, Mohan Kumar R, Agrawal A, Dubey GP. Anticancer activity of Moringa oleifera mediated silver nanoparticles on human cervical carcinoma cells by apoptosis induction. Colloids Surf B. 2014;117:354-9.

Rafie HM, Hamed MA. Antioxidant and anti-inflammatory activities of silver nanoparticles biosynthesized from aqueous leaves extracts of four Terminalia species. Adv Nat Sci Nanosci Nanotechnol. 2014;5:1-11.

Bhuvaneswari R, Chidambaranathan N, Jegatheesan K. Hepatoprotective effect of Embilica officinalis and its silver nanoparticles against ccl4 induced hepatotoxicity in wistar albino rats. Dig J Nanomater Biostruct. 2014;9:223-35.

Kaler A, Mittal AK, Katariya M, Harde H, Agrawal AK, Jain S, et al. An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles. J Nanopart Res. 2014;16:2605

Hu R, Yong KT, Roy I, Ding H, He S, Prasad PN. Metallic nanostructures as localized plasmon resonance enhanced scattering probes for multiplex dark field targeted imaging of cancer cells. J Phys Chem C. 2009;113:2676–84.

Yin B, Ma H, Wang S, Chen S. Electrochemical synthesis of silver nanoparticles under protection of polyN-vinylpyrrolidone. J Phys Chem B. 2003;107:8898–904.

Dimitrijevic NM, Bartels DM, Jonah CD, Takahashi K, Rajh T. Radiolytically induced formation and optical absorption spectra of colloidal silver nanoparticles in supercritical ethane. J Phys Chem B 2001;105:954–9.

Wang S, Zhang Y, Ma HL, Zhang Q, Xu W, Peng J, et al. Ionic-liquid-assisted facile synthesis of silver nanoparticle-reduced graphene oxide hybrids by gamma irradiation. Carbon 2013;55:245-52.

Callegari A, Tonti D, Chergui M. Photochemically grown silver nanoparticles with wavelength-controlled size and shape. Nano Lett. 2003;3:1565–8.

Pandey S, Goswami GK, Nanda KK. Green synthesis of biopolymer–silver nanoparticle nanocomposite: An optical sensor for ammonia detection. ‎Int J Biol Macromolec. 2012;51:583-9.

Gopinathan P, Ashok AM, Selvakumar R. Bacterial flagella as biotemplate for the synthesis of silver nanoparticle impregnated bionanomaterial. Appl Surf Sci. 2013;276:717-22.

Marimuthu S, Abdul Rahuman A, Rajakumar G, Santhoshkumar T, Kirthi AV, Jayaseelan C, et al. Evaluation of green synthesized silver nanoparticles against parasites. Parasitol Res. 2011;108:1541–9.

Nayak RR, Pradhan N, Behera D, Pradhan KM, Mishra S, Sukla LB, et al. Green synthesis of silver nanoparticle by Penicillium purpurogenum NPMF: the process and optimization. J Nanopart Res. 2011;13:3129–37.

Ahmad N, Sharma S. Green synthesis of silver nanoparticles using extracts of Ananas comosus. Green Sustain Chem. 2012;2:141-7.

Sivaraman SK, Elango I, Kumar S, Santhanam V. A green protocol for room temperature synthesis of silver nanoparticles in seconds. Curr Sci. 2009;97:1055–59.

Martínez-Castañón GA, Niño-Martínez N, Martínez-Gutierrez F, Martínez-Mendoza JR. Synthesis and antibacterial activity of silver nanoparticles with different sizes. J Nanopart Res. 2008;10:1343–8.

Lok CN, Ho CM, Chen R, He QY, Yu WY, Sun H, et al. Silver nanoparticles: partial oxidation and antibacterial activities, J Biol Inorg Chem. 2007;12:527–34.

Zahir AA, Chauhan IS, Bagavan A, Kamaraj C, Elango G, Shankar J, et al. Green Synthesis of Silver and Titanium Dioxide Nanoparticles Using Euphorbia prostrata Extract Shows Shift from Apoptosis to G0/G1 Arrest followed by Necrotic Cell Death in Leishmania donovani. Antimicrob Agents Chemother. 2015;59:4782–99.

Singh P, Kim YJ, Wang C, Mathiyalagan R, El-Agamy Farh M, Yang DC. Biogenic silver and gold nanoparticles synthesized using red ginseng root extract, and their applications. Artif Cells Nanomed Biotechnol. 2016;44:811-6.

Poopathi S, De Britto LJ, Praba VL, Mani C, Praveen M. Synthesis of silver nanoparticles from Azadirachta indica—a most effective method for mosquito control. Environ Sci Pollut Res. 2015;22:2956–63.

Amooaghaie R, Saeri MR, Azizi M. Synthesis, characterization and biocompatibility of silver nanoparticles synthesized from Nigella sativa leaf extract in comparison with chemical silver nanoparticles. Ecotoxicol Environ Saf. 2015;120:400-8.

Sadeghi B, Rostami A, Momeni SS. Facile green synthesis of silver nanoparticles using seed aqueous extract of Pistacia atlantica and its antibacterial activity. Spectrochim Acta A Mol Biomol Spectrosc. 2015;134:326–32.

Kora AJ, Beedu SR, Jayaraman A. Size-controlled green synthesis of silver nanoparticles mediated by gum ghatti Anogeissus latifolia. and its biological activity. Org Med Chem Lett. 2012;2:17.

Padalia H, Moteriya P, Chanda S. Green synthesis of silver nanoparticles from marigold flower and its synergistic antimicrobial potential. Arab J Chem. 2015;8:732-41.

Patil CD, Patil SV, Borase HP, Salunke BK, Salunkhe RB. Larvicidal activity of silver nanoparticles synthesized using Plumeria rubra plant latex against Aedes aegypti and Anopheles stephensi. Parasitol Res. 2012;110:1815-22.

Suganya A, Murugan K, Kovendan K, Kumar PM, Hwang JS. Green synthesis of silver nanoparticles using Murraya koenigii leaf extract against Anopheles stephensi and Aedes aegypti. Parasitol Res. 2013;112:1385–97.

Satyavani K, Gurudeeban S, Ramanathan T, Balasubramanian T. Biomedical potential of silver nanoparticles synthesized from calli cells of Citrullus colocynthis (L.) Schrad. J Nanobiotechnology. 2011;9:43

Sathishkumar P, Vennila K, Jayakumar R, Yusoff AR, Hadibarata T, Palvannan T. Phyto-synthesis of silver nanoparticles using Alternanthera tenella leaf extract: an effective inhibitor for the migration of human breast adenocarcinoma MCF-7 cells. Bioprocess Biosyst Eng. 2016;39:651-9.

Marimuthu S, Rahuman AA, Rajakumar G, Santhoshkumar T, Kirthi AV, Jayaseelan C, et al. Evaluation of green synthesized silver nanoparticles against parasites. Parasitol Res. 2011;108:1541-9.

Rashidipour M, Heydari R. Biosynthesis of silver nanoparticles using extract of olive leaf: synthesis and in vitro cytotoxic effect on MCF-7 cells. J Nanostruct Chem. 2014;4:112.

Heydari R, Rashidipour M. Green Synthesis of Silver Nanoparticles Using Extract of Oak Fruit Hull Jaft.: Synthesis and in vitro cytotoxic effect on MCF-7 cells. Int J Breast Cancer. 2015;Article ID 846743.

Ali MS, Altaf M, Al-Lohedan HA. Green synthesis of biogenic silver nanoparticles using Solanum tuberosum extract and their interaction with human serum albumin: Evidence of “corona” formation through a multi-spectroscopic and molecular docking analysis. J Photochem Photobiol B. 2017;173:108-19.

Shankar S, Leejae S, Jaiswal L, Voravuthikunchai SP. Metallic nanoparticles augmented the antibacterial potency of Rhodomyrtus tomentosa acetone extract against Escherichia coli. Microb Pathog. 2017;107:181-4.

Naraginti S, Li Y. Preliminary investigation of catalytic, antioxidant, anticancer and bactericidal activity of green synthesized silver and gold nanoparticles using Actinidia deliciosa. J Photochem Photobiol B. 2017;170:225–34.

Banerjee PP, Bandyopadhyay A, Harsha SN, Policegoudra RS, Bhattacharya S, Karak N, Chattopadhyay A. Mentha arvensis Linn..-mediated green silver nanoparticles trigger caspase 9-dependent cell death in MCF7 and MDA-MB-231 cells. Breast Cancer: Targets and Therapy. 2017;9:265-78.

Rajathi P, Suja S. Biomimetic synthesis, characterization and evaluation of antioxidant, antimicrobial efficacy of silver nanoparticles using anredera cordifolia leaf extract. Asian J Pharm Clin Res. 2017;10:329-34.

Jayaprakash N, Vijaya JJ, Kaviyarasu K, Kombaiah K, Kennedy LJ, Ramalingam RJ, et al. Green synthesis of Ag nanoparticles using Tamarind fruit extract for the antibacterial studies. J Photochem Photobiol B. 2017;169:178-85.

Dehghanizade S, Arasteh J, Mirzaie A. Green synthesis of silver nanoparticles using Anthemis atropatana extract: characterization and in vitro biological activities. Artif Cells Nanomed Biotechnol. 2017, DOI: 10.1080/21691401.2017.1304402.

Asha S, Asha A, Rajeshkumar S. Evaluation of phytochemical constituents and antimicrobial activity of silver nanoparticle synthesized ipomoea nil against selected pathogens. Asian J Pharm Clin Res. 2017;10:183-7.

Patra JK, Baek KH. Antibacterial activity and synergistic antibacterial potential of biosynthesized silver nanoparticles against foodborne pathogenic bacteria along with its anticandidal and antioxidant effects. Front Microbiol. 2017;8:167.

Venugopal K, Rather HA, Rajagopal K, Shanthi MP, Sheriff K, Illiyas M, et al. Synthesis of silver nanoparticles Ag NPs for anticancer activities MCF 7 breast and A549 lung cell lines of the crude extract of Syzygium aromaticum. J Photochem Photobiol B. 2017;167:282–9.

Prasannaraj G, Venkatachalam P. Hepatoprotective effect of engineered silver nanoparticles coated bioactive compounds against diethylnitrosamine induced hepatocarcinogenesis in experimental mice. J Photochem Photobiol B. 2017;167:309–20.

Rajakumar G, Gomathi T, Thiruvengadam M, Rajeswari VD, Kalpana VN, Chung M. Evaluation of anti-cholinesterase, antibacterial and cytotoxic activities of green synthesized silver nanoparticles using from Millettia pinnata flower extract. Microb Pathog. 2017;103:123-8.

Singh AK, Tiwari R, Kumar V, Singh P, Riyazat Khadim SK, Tiwari A, et al. Photo-induced biosynthesis of silver nanoparticles from aqueous extract of Dunaliella salina and their anticancer potential. J Photochem Photobiol B. 2017;166:202–11.

Su HL, Chou CC, Hung DJ, Lin SH, Pao IC, Lin JH,et al. The disruption of bacterial membrane integrity through ROS generation induced by nanohybrids of silver and clay. Biomater. 2009;30:5979–87.

Gordon O, Slenters TV, Brunetto PS, Villaruz AE, Sturdevant DE, Otto M, et al. Silver coordination polymers for prevention of implant infection: thiol interaction, impact on respiratory chain enzymes, and hydroxyl radical induction. Antimicrob Agents Chemother. 2010;54: 4208-18.

Hossain Z, Huq F. Studies on the interaction between Cd2+ ions and nucleobases and nucleotides. J Inorgan Biochem. 2002;90:97-105.

David L, Moldovan B, Vulcu A, Olenic L, Perde-Schrepler M, Fischer-Fodor E, et al. Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract. Colloids Surf B. 2014;122:767–77.

Ramar M, Manikandan B, Raman T, Arunagirinathan K, Prabhu NM, Basu MJ, et al. Biosynthesis of silver nanoparticles using ethanolic petals extract ofRosa indicaand characterization of its antibacterial, anticancer and anti-inflammatory activities. Spectrochim Acta A Mol Biomol Spectrosc. 2015;138:120–9.

Rajakumar G, Rahuman AA. Larvicidal activity of silver nanoparticles using Eclipta prostrata leaf extract against filariasis and malaria vectors. Acta Trop. 2011;118:196–203.

Section
Review Article