Lorestan University of Medical SciencesHerbal Medicines Journal2538-21449120240501A Short Review of Allium jesdianum Boiss. & Buhse (Amaryllidaceae)11722095110.22087/hmj.v9i1ENSaeedMohsenzadehDepartment of Biology, Kazerun Branch, Islamic Azad University, Kazerun, IranJournal Article20250517Allium jesdianum Boiss. & Buhse (Bon-e-Sorkh or Yazdi onion in Persian) is one of Iran's important endemic and threatened plants belonging to the genus Allium. It grows at high altitudes (1800‒2600 m) in Zagros Mountains, where locals use the bulbs and aerial parts of the plant to treat colds, stomachaches, rheumatic pains,moisture diseases, and kidney problems. There is little research that highlights the chemical composition and biological activities of this medicinal herb. This review outlines the available literature on morphological characteristics, chemical composition, and medicinal uses of the A. jesdianum. Google Scholar, PubMed,Scopus, Web of Science, and local databases were searched to find relevant articles published in these databases from 1996 to 2023. Various climatic and environmental factors can affect the chemical composition of A.jesdianum. Bon-e-Sorkh possesses several medicinally significant activities such as antioxidant, anti-inflammatory, analgesic, antidiabetic, antibacterial, antifungal, anti-hepatic, anti-nephrotoxicity, anticancer,anti-Alzheimer's, antiplatelet, anti-anxiolytic, nephrolithiasis, protoscolicidal, and anti-toxicity activities. Investigators should complete further research to prove or confirm the results of previous studies reported in this paper by conducting more in vitro studies, and then in vivo as well as clinical studies if the results are promisinghttps://hmj.lums.ac.ir/article_220951_3b08260d7a69e79a1e1822dd449e6091.pdfLorestan University of Medical SciencesHerbal Medicines Journal2538-21449120240501Comparing the Cost-Effectiveness of Herbal Medicines with Chemical Medicines1622095210.22087/hmj.v9i1.1060ENHadiHayatiRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
Department of Pharmacoeconomics and Management, School of Pharmacy, Lorestan University of Medical Sciences, Khorramabad,
IranJournal Article20250517Herbal medicines and chemical medicines are both commonly used in the treatment of a variety of ailments. However, the cost-effectiveness of these remedies has remained a controversial topic. This review aims to compare the cost-effectiveness of herbal medicines to chemical medicines. Likewise, a comprehensive search was conducted on reputable databases, including PubMed, Web of Science, and Scopus, using relevant keywords. The search methodology encompassed the utilization of specific Medical Subject Headings (MeSH) terms, namely "herbal medicine," "plant extracts," "phytotherapy," "cost-benefit analysis," "cost savings," "economics, pharmaceutical," "comparative effectiveness research," "therapeutics," "pharmaceutical preparations," and "chemistry, pharmaceutical." The search was restricted to articles published in English within the time span of January 2010 to December 2022.The selection process involved both systematic and subjective approaches, with the most relevant articles identified based on the researcher's expertise. Out of the initial 41 articles, only 9 were found to be eligible for inclusion in the study after a thorough analysis. Thus, only a few studies met the criteria for inclusion in this review. The results indicated that herbal medicines possess the capacity to offer economically viable alternatives to conventional pharmaceuticals. However, the diversity in research methodologies and outcomes poses challenges in establishing conclusive findings. It is noteworthy that while herbal medicines are more cost-effective, they may also induce side effects that are contingent upon the specific herb and the individual's health condition. Consequently, the inclusion of adverse effects associated with herbal medicines and plant extracts should be considered when conducting cost-effectiveness analyses. https://hmj.lums.ac.ir/article_220952_85fe9a5d455e3ddac869e5dd14aaeaa6.pdf