Herbal Medicines Journal
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Scolicidal Effect of Some Herbs on Echinococcus granulosus Protoscoleces: a Systematic Literature Review

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Authors

Ali Rostami 1
Mojtaba Taheri 2
Majid Gholizadeh 3
Seyyed Javad Seyyedtabaei 1
Saber Raeghi 4
Shirzad Fallahi 5

1 1 Department of Parasitology and Mycology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Faculty of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 Department of Microbiology, Khazar University, Mahmood Abad, Iran

4 Department of Laboratory Science, Maragheh University of Medical Sciences, Maragheh, Iran

5 5 Department of Parasitology and Mycology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran 6Razi Herbal Medicines Research Center, Lorestan University of Medical Science, Khorramabad, Iran

10.22087/hmj.v1i1.565
Abstract
Surgery is the best choice of treatment for human hydatidosis. Secondary infection is one of the end points of surgery in treating the hydatidosis which results from the spillage of protoscolices into the peritoneal cavity. Many chemical scolicidal agents have been used for inactivation of the cyst’s content, but most of them are associated with adverse side effects. Some studies have reported that traditional plants might have a potential application in prevention of post-surgery infections. We searched Medline, PubMed and Google scholar to identify the potentially relevant studies on implication of traditional plants against Echinococcus granulosus protoscoleces. In this study, we have reviewed scolicidal effects of some plant species (such as Zataria multiflora, Berberis vulgaris, Allium spp. Mentha spp. and etc.) and their products (essential oils, methanolic extract, aqueous extract and etc.) on Echinococcus granulosus protoccoleces. The scolicidal activity of these herbs could be helpful in hydatid cyst surgery. However, the mechanisms by which plant extracts killed protoscolices and also their safety for human cells are unclear and needed to be more investigated.

Keywords

Herbs
Scolicidal effect
Hydatidosis
Surgery
Herbal Medicines Journal
Volume 1, Issue 1
Spring 2016
Pages 53-59

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